GREEN TEA EXTRACT: POLYPHENOLS -
CATECHINS (EGCG – EGC – ECG – EC – GCG)
Research and Studies
Researchers have discovered that a component in green tea helps kill cells of the most common leukemia in the United States. The research using laboratory cell cultures shows that a component of green tea known as epigallocatechin-3-gallate (EGCG) [epi-gallo-cat-ekin-3-gal-ate] helps kill leukemia cells by interrupting the communication signals they need to survive.Mayo Clinic
• The researchers suggest that green tea extracts, which are relatively non-toxic, may be beneficial in the treatment of patients with head and neck cancers. Further studies are necessary to determine the proper dosage of the extract. Dr. Masuda presented these findings at the International Society of Preventive Oncology meeting in February. The research was published in December 2001 in Clinical Cancer Research.
• EGCG may also inhibit other types of cancers via other growth factor receptors. Recent evidence from Drs. Masuda and Weinstein indicates that EGCG inhibits HER2-neu activity in breast cancer cell lines; this natural product, therefore, may also be useful in treating patients with breast cancer. The National Foundation for Cancer Research, the T.J. Martell Foundation, and the Richard and Hinda Rosenthal Center for Complementary and Alternative Medicine sponsored this research.
• Several components of green tea leaves are known to have natural properties that counteract the harmful effects of oxidation in the blood. In fact, the principal and most powerful of these catechins or flavonoids, EGCG (epigallocatechin-3-gallate), has been shown to provide some protection against the development of inflammation, tumors and the new blood vessels that support tumor growth. Because of the antioxidant properties of the catechins in its leaves, tea also has been seen as a potential dietary intervention for cardiovascular diseases. Oxidation, which damages the inner surfaces of arteries and encourages the formation of plaque deposits, is believed to be one factor in the development of atherosclerosis. Cedars-Sinai Medical Center.
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